The most common genetic mutations in breast cancer occur in the BRCA 1 and BRCA 2 genes, but there are other genes associated with breast cancer. When BRCA 1/2 mutates, it increases the risk of breast cancer or other cancers, such as ovarian cancer and prostate cancer.
BRCA1/2 gene mutation belongs to dominant inheritance and has the opportunity to be inherited from father or mother. Simply put, whether BRCA mutants are male or female, they have a 50% chance of passing on the BRCA mutation to the next generation.
The frequency of breast cancer screening recommended for each person may not be the same. People with genetic risk of breast cancer should conduct breast cancer screening more frequently than the general public. You can refer to the following recommended procedures issued by the National Comprehensive Cancer Institute (NCCN).
|Screening Method||Population Risk||Hereditary Risk|
|Clinical Examination||Once a year||Every 6-12 months|
|Mammogram||Once a year||Once a year (or breast MRI scan)|
|Sonography Screening||No related suggestion||No related suggestion|
|Breast MRI Scan||No related suggestion||Once a year (or mammogram)|