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CoGenesis™ 癌症基因测试

什麽是CoGenesis™ 癌症基因测试?

CoGenesis™ 癌症基因测试针对肿瘤组织进行准确的分子分析。 通过使用新一代基因图谱排序 (NGS),CoGenesis™ 癌症基因测试可检测癌症基因的异常,这些癌症基因是诱发癌症的原因。因此, 我们积极开发药物基因组学数据库,让CoGenesis™ 癌症基因测试分析为你寻找诱发癌症的变异基因,也协助医生能够为癌症患者提供精准个人化的临床诊治。

为什麽我们建议CoGenesis™ 癌症基因测试?

CoGenesis™ 癌症基因测试平台为癌症患者提供快速临床诊断结果。

CoGenesis™ 癌症基因测试的好处

  • 提供定制的标靶治疗和免疫治疗建议
  • 减少潜在的副作用,缩短恢复时间
  • 确认肿瘤基因,以便更准确地进行临床诊断

谁应该考虑CoGenesis™ 癌症基因测试?

  • 正在考虑标靶治疗或免疫疗法的患者
  • 对常规癌症疗法效果不明显的患者
  • 临床医生要求对肿瘤基因进行分析以便提供精准治疗

 

Evidences

  • CRC: pembrolizumab reported to have 72% 2-year overall survival in adults with treatment refractory metastatic mismatch repair-deficient colorectal cancer [1]
  • Lung cancer: first-line treatment with EGFR tyrosine kinase inhibitors is associated with improved progression free survival compared to platinum-based doublet chemotherapy in adults with EGFR mutation and stage IIIB-IV non-small cell lung cancer [2]. ROS1 gene must be performed in all lung adenocarcinoma. BRAF, RET, HER2, KRAS, MET should be tested if routine EGFR, ALK, and ROS1 testing are negative [3].
  • Breast cancer: Genetic testing should be made available to all newly diagnosed breast cancer patient. Testing should not be limited to BRCA1/2 [4]

 

确定肿瘤类型
(多种癌症诊断结果)
伴随式诊断
(分子生物标记)

如何为自己或家人订购药物基因测试?

CoGenesis™ Cancer 可以从我们合作伙伴的诊所订购。请联系我们获取更多信息。

Reference

[1] Dung T.L.E. et. al, A pan-cancer biomarker is identified that can predict successful response to cancer immunotherapy in human patients. Science, 2017; 28 JUL 2017 pp 409-413

[2] Gao G. et al ., Epidermal growth factor receptor-tyrosine kinase inhibitor therapy is effective as first-line treatment of advanced non-small-cell lung cancer with mutated EGFR: A meta-analysis from six phase III randomized controlled trials. Int. J. Cancer, 2012; 131: E822-E829

[3] Kalemkerian, G et. al., Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors: American Society of Clinical Oncology Endorsement Summary of the College of American Pathologists/International Association for the Study of Lung Cancer/Association for Molecular Pathology Clinical Practice Guideline Update. Journal Of Oncology Practice, 2018; 14(5), 323-327

[4] The American Society of Breast Surgeon, Consensus Guideline on Genetic Testing for Hereditary Breast Cancer, 2018