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Cancer Monitoring

Cxbladder® Monitor

De-intensify the surveillance of non-muscle invasive bladder cancer.

Turnaround Time5 working days from laboratory receiving sample
🧪Specimen TypeUrine
🔬MethodRT-qPCR
AccreditationsCLIA certified and ISO 15189 accredited
Cxbladder® Monitor

Cxbladder Monitor is a non-invasive surveillance alternative that can reduce the burden of repeated cystoscopy in non-muscle invasive bladder cancer (NMIBC) patients with a low risk of recurrent disease, improving comfort and compliance.

• Combines both genotypic factors and patient clinical information to reliably rule out those patients with a low probability of urothelial cancer, reducing the frequency of cystoscopy required.

• Spares patients the discomfort, anxiety, risk, and inconvenience of an invasive procedure.

• Improves compliance with scheduled surveillance checks.

• Focuses your in-clinic resources on those that need care.

• Empowers your team and improve time utilisation to maximise overall efficiency.

⚠ Not intended for:

Not for first-line diagnosis of bladder cancer. Not for high-grade or muscle-invasive bladder cancer surveillance without cystoscopy. Not a replacement for cystoscopy where clinical concern is present.

CDC2IGFBP5HOXA13MDKCXCR2
Step / TestAccuracyNotes
Sensitivity93%
NPV97%
Specimen Type: Urine
Preferred Collection:

Urine in Cxbladder container

30–50 mL midstream urine collected into the Cxbladder collection tube (contains preservative). Do not use catheter samples.

Rejection Criteria:
  • First void urine (Only 2nd pass of the day or later is accepted)
  • Grossly bloody urine
  • Acute UTI (Treat UTI first and delay test for 2 weeks)
  • <2 weeks after cystoscopy
  • <6 weeks after BCG

Available through Codex Genetics as the authorised Pacific Edge distributor in Hong Kong.

Shipping Instructions:

Cxbladder specimens must be collected using the dedicated Cxbladder collection kit.

  1. Request a collection kit from your healthcare provider or Codex Genetics.
  2. Collect midstream urine (30–50 mL) into the provided tube with preservative.
  3. Seal securely; store at room temperature.
  4. Deliver to Codex Genetics Laboratory within 5 days of collection. Address: Unit 220, 2/F, Building 16W, HKSTP, Pak Shek Kok, NT, Hong Kong.

Please contact us for pricing.

  • Cxbladder Monitor Score < 3.5
    • Low probability of recurrent urothelial carcinoma
  • Cxbladder Monitor Score >= 3.5
    • Cannot rule out urothelial carcinoma and a clinician-directed protocol to determine if recurrent Urothelial Carcinoma is present is warranted

NMIBC accounts for ~75% of bladder cancer cases. Standard surveillance requires regular cystoscopy, which is invasive, costly, and burdensome for patients. Published clinical studies show Cxbladder Monitor has high sensitivity for detecting recurrence, enabling clinicians to alternate with or substitute cystoscopy in appropriate patients.