Is Hereditary Breast Cancer Common?
Genetic inheritance plays an important role in the development of breast cancer. About 10% of patients have inherited mutated genes. Patients with breast cancer gene mutations have a 10-fold higher chance of developing breast cancer. The most common genetic mutations in breast cancer occur in the BRCA 1 and BRCA 2 genes. When BRCA 1 & 2 mutates, it increases the risk of breast cancer or even other cancers, such as ovarian cancer and prostate cancer.
BRCA 1 & 2 gene mutations are inherited in an autosomal dominant manner, meaning if the child gets the abnormal gene from only one parent, the child will inherit the mutated gene and has a higher risk of getting cancer. Whether the BRCA gene mutation is found in a male or a female, it has a 50% chance of inheriting the BRCA 1 & 2 gene mutation to the next generation.