Van Cauwenberghe, C., Van Broeckhoven, C. & Sleegers, K. The genetic landscape of Alzheimer disease: clinical implications and perspectives. Genet Med 18, 421–430 (2016).
Porter, T., Gozt, A.K., Mastaglia, F.L. and Laws, S.M. (2019). The Role of Genetics in Alzheimer's Disease and Parkinson's Disease. In Neurodegeneration and Alzheimer's Disease.
|Alzheimer’s Disease-related tests|
|CoGenesis® AD||APOE test|
|Gene tested||APP, PSEN1, PSEN2, APOE, TREM2, MAPT||APOE|
|Target of service||
|Variant calling – SNP||>99%*#|
|Variant calling – Indel||>99%*#|
* Passed GenQA/UK NEQAS external quality assurance
# The interpretation of sequencing variants is based on the current understanding of the variants at the time it was observed, which may change over time as more information about the genes becomes available. Not all variants are represented in this report.