Drug response genetic testing

Optimizing medication

Our genetic makeup affects how we absorb, metabolize, and respond to drugs. This test delivers a comprehensive report in just 6 weeks, helping to determine the dosage and drug type that will work best for an individual.

Nearly all HK Chinese (99.6%) have at least one pharmacogenetic variant.

Yu MHC, Chan MCY, Chung CCY, Li AWT, Yip CYW, Mak CCY, et al. (2021) Actionable pharmacogenetic variants in Hong Kong Chinese exome sequencing data and projected prescription impact in the Hong Kong population.

What is Pharmacogenomics (PGx)?

  • Helps reduce adverse drug reactions and complications​
  • Informs optimized dosage​
  • Suggest treatment alternatives for patients who experienced treatment failures​
  • Reduce costs on ineffective treatments

From heart disease to depression

Genetic screening can be hugely beneficial when it comes to treating a range of conditions requiring medication, including cardiovascular diseases and even depression.

Find what works

We are all genetically different. These differences can explain our susceptibility to disease, and how we respond to medication.

The process

1

Order and receive a saliva collection kit.

2

Register the sample collection tube barcode online, then take a sample.

3

Mail the kit back to Codex’s laboratory for analysis.

4

Results are provided to you securely on the Codex website within six weeks from receipt of sample.

A high accuracy standard

Steps Accuracy
DNA sequencing 99.9%
Variant calling – SNP >99%*
Variant calling – Indel >99%*
Variant Annotation 100%#

* Passed GenQA/UK NEQAS external quality assurance

# The interpretation of sequencing variants is based on the current understanding of the variants at the time it was observed, which may change over time as more information about the genes becomes available. Not all variants are represented in this report.

Disclaimer:
The interpretations and clinical annotations provided by Codex are intended solely for use by a medical professional and do not constitute medical advice by Codex. Test results shown on this report require clinical interpretation and comments by a specialist of the respective discipline. The pharmacokinetics of a drug might be affected by the dosage form and route of administration. Please consult a qualified healthcare professional before making decisions about medical conditions or before starting and stopping any prescribed treatment. The treating providers are ultimately responsible for all diagnoses and treatments. The report and recommendations are based on the guidelines provided by CPIC1 and do not take into account other genetic variants and environmental or social factors that may affect the drug response. Other factors not included in this report include, but are not limited to, environmental factors (e.g., smoking), health factors (e.g., diet), social factors, various medical conditions, and other concurrent medications. Off-label drug uses are not considered in this report. The recommendations in the report are for the corresponding drugs only, and the drug-drug interactions are not considered. As a matter of practice, Codex will routinely update its database as new information becomes available to the scientific community. Annotations and recommendations are therefore dependent on the date of generation and/or the database version used to generate that report.