CoGenesis® Prostate is an 11-gene test for hereditary prostate cancers. It
includes genes linked to a higher chance of developing prostate cancer:
ATM, BRCA1, BRCA2, CHEK2, EPCAM, MLH1, MSH2, MSH6, NBN, PMS2, TP53 genes.
It helps you to understand your risk level of developing prostate cancer
throughout your lifetime.
If you have a prostate cancer gene mutation, your chance of getting
prostate cancer is 5 to 7 times higher than the general
population. 2
If you have 1 close relative with prostate cancer, your chance of
getting prostate cancer is 2 to 3 times higher than the
general population. 3
Familial prostate cancer makes up about 20% of all prostate
cancer. 3
If you have tested positive for a prostate cancer gene mutation, it
does not mean you definitely will have prostate cancer. However, your
chance of getting prostate cancer will be higher than the general
population.
What can you do if you belong to the high-risk population?
Start prostate cancer screening tests as soon as possible
Screen for prostate cancer more frequently
Closely watch out for any prostate cancer symptoms
Learn about options that reduce prostate cancer risk
Not only in elderly men
Men with a prostate cancer gene mutation are prone to developing
prostate cancer at a younger age
Prostate cancer patients with prostate cancer gene mutations can
receive more extensive and early treatment than other patients
Prostate cancer gene mutation carriers should consider beginning PSA
screening at age 40, and screening at annual intervals.
NCCN Genetic/Familial High-Risk Assessment: Breast, Ovarian, and
Pancreatic (Version 1.2020)
# The interpretation of sequencing variants is based on the current
understanding of the variants at the time it was observed, which may change
over time as more information about the genes becomes available. Not all
variants are represented in this report.
Source:
American Cancer Society. Prostate Cancer Causes, Risk Factors, and
Prevention.
Cancer Research UK. Prostate Cancer Risk, Family history and genetic
factors.
